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1

Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine Sponge Theonella swinhoei

Sepe, Valentina, Ummarino, Raffaella, D’Auria, Maria Valeria, Chini, Maria Giovanna, Bifulco, Giuseppe, Renga, Barbara, D’Amore, Claudio, Debitus, Cécile, Fiorucci, Stefano, Zampella, Angela

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.76 MB

english, 2012

2

Natural Ligands for Nuclear Receptors: Biology and Potential Therapeutic Applications

Valeria D'Auria, Maria, Sepe, Valentina, Zampella, Angela

Journal:

Current Topics in Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 667 KB

english, 2012

3

Stereochemical Studies on Sphinxolide: Advances in the J-Based NMR Determination of the Relative Configuration of Flexible Systems

Carla Bassarello, Giuseppe Bifulco, Angela Zampella, Maria Valeria D’Auria, Raffaele Riccio, Luigi Gomez-Paloma

Journal:

European Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 413 KB

english, 2001

4

Stereochemistry of Sphinxolides and Reidispongiolides. Asymmetric Synthesis of the C17−C22 Fragment of Reidispongiolide A

Angela Zampella, Carla Bassarello, Giuseppe Bifulco, Luigi Gomez-Paloma, Maria Valeria D'Auria

Journal:

European Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 446 KB

english, 2002

5

Cover Picture

Angela Zampella, Carla Bassarello, Giuseppe Bifulco, Luigi Gomez-Paloma, Maria Valeria D'Auria

Journal:

European Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 147 KB

english, 2002

6

The Molecular Mechanism of Bee Venom Phospholipase A2 Inactivation by Bolinaquinone

Maria Chiara Monti, Agostino Casapullo, Cosima Santomauro, Maria Valeria D'Auria, Raffaele Riccio, Luigi Gomez-Paloma

Journal:

Year:

2006

Language:

english

File:

PDF, 319 KB

english, 2006

7

ChemInform Abstract: Crellastatin A: A Cytotoxic Bis-Steroid Sulfate from the Vanuatu Marine Sponge Crella sp.

Maria Valeria D'Auria, Clelia Giannini, Angela Zampella, Luigi Minale, Cecile Debitus, Christos Roussakis

Journal:

Year:

1999

File:

PDF, 28 KB

1999

8

ChemInform Abstract: Isolation and Structural Elucidation of the Crellastatins I-M: Cytotoxic Bis-Steroid Derivatives from the Vanuatu Marine Sponge Crella sp.

Clelia Giannini, Angela Zampella, Cecile Debitus, Jean-Louis Menou, Christos Roussakis, Maria Valeria D'Auria

Journal:

Year:

2000

File:

PDF, 25 KB

2000

9

ChemInform Abstract: Dysidotronic Acid, a New and Selective Human Phospholipase A2 Inhibitor from the Sponge Dysidea sp.

Clelia Giannini, Cecile Debitus, Inmaculada Posadas, Miguel Paya, Maria Valeria D'Auria

Journal:

Year:

2000

File:

PDF, 30 KB

2000

10

ChemInform Abstract: Amphiasterins: A New Family of Cytotoxic Metabolites from the Marine Sponge Plakortis quasiamphiaster

Angela Zampella, Clelia Giannini, Cecile Debitus, Maria Valeria D'Auria

Journal:

Year:

2001

File:

PDF, 28 KB

2001

11

ChemInform Abstract: Studies Towards the Synthesis of Superstolide A (I). Synthesis and Stereochemical Assignment of the C(21)—C(26) Fragment (II) of Superstolide A.

Angela Zampella, Maria Valeria D'Auria

Journal:

Year:

2001

File:

PDF, 26 KB

2001

12

ChemInform Abstract: Isolation of Callipeltins A—C and of Two New Open-Chain Derivatives of Callipeltin A from the Marine Sponge Latrunculia sp. A Revision of the Stereostructure of Callipeltins.

Angela Zampella, Antonio Randazzo, Nicola Borbone, Sisto Luciani, Lucia Trevisi, Cecile Debitus, Maria Valeria D'Auria

Journal:

Year:

2002

File:

PDF, 28 KB

2002

13

ChemInform Abstract: Coscinolactams A and B: New Nitrogen-Containing Sesterterpenoids from the Marine Sponge Coscinoderma mathewsi Exerting Antiinflammatory Properties.

Simona De Marino, Carmen Festa, Maria Valeria D'Auria, Marie-Lise Bourguet-Kondracki, Sylvain Petek, Cecile Debitus, Rosa Maria Andres, Maria Carmen Terencio, Miguel Paya, Angela Zampella

Journal:

Year:

2009

File:

PDF, 15 KB

2009

14

ChemInform Abstract: Solomonamides A and B, New Antiinflammatory Peptides from Theonella swinhoei.

Carmen Festa, Simon De Marino, Valentina Sepe, Maria Valeria D'Auria, Giuseppe Bifulco, Cecile Debitus, Mariarosaria Bucci, Valentina Vellecco, Angela Zampella

Journal:

Year:

2011

File:

PDF, 22 KB

2011

15

Isolation of Plakinamine I: A New Steroidal Alkaloid from the Marine Sponge Corticium sp. and Synthesis of an Analogue Model Compound

Angela Zampella, Rosa D'Orsi, Valentina Sepe, Simona De Marino, Nicola Borbone, Alexis Valentin, Cécile Debitus, Franco Zollo, Maria Valeria D'Auria

Journal:

European Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

16

Quantum Mechanical Calculation of Coupling Constants in the Configurational Analysis of Flexible Systems: Determination of the Configuration of Callipeltin A

Carla Bassarello, Angela Zampella, Maria Chiara Monti, Luigi Gomez-Paloma, Maria Valeria D’Auria, Raffaele Riccio, Giuseppe Bifulco

Journal:

European Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

17

Callipeltins F–I: new antifungal peptides from the marine sponge Latrunculia sp.

Valentina Sepe, Rosa D'Orsi, Nicola Borbone, Maria Valeria D'Auria, Giuseppe Bifulco, Maria Chiara Monti, Anna Catania, Angela Zampella

Journal:

Year:

2006

Language:

english

File:

PDF, 140 KB

english, 2006

18

Isolation and structural elucidation of callipeltins J–M: antifungal peptides from the marine sponge Latrunculia sp.

Maria Valeria D'Auria, Valentina Sepe, Rosa D'Orsi, Filomena Bellotta, Cécile Debitus, Angela Zampella

Journal:

Year:

2007

Language:

english

File:

PDF, 335 KB

english, 2007

19

New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans

Fulvio Gala, Maria Valeria D'Auria, Simona De Marino, Franco Zollo, Charles D. Smith, Jean E. Copper, Angela Zampella

Journal:

Year:

2007

Language:

english

File:

PDF, 459 KB

english, 2007

20

Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans

Fulvio Gala, Maria Valeria D'Auria, Simona De Marino, Valentina Sepe, Franco Zollo, Charles D. Smith, Jean E. Copper, Angela Zampella

Journal:

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

21

Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Fulvio Gala, Maria Valeria D'Auria, Simona De Marino, Valentina Sepe, Franco Zollo, Charles D. Smith, Staci N. Keller, Angela Zampella

Journal:

Year:

2009

Language:

english

File:

PDF, 245 KB

english, 2009

22

Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties

Simona De Marino, Carmen Festa, Maria Valeria D'Auria, Marie-Lise Bourguet-Kondracki, Sylvain Petek, Cecile Debitus, Rosa María Andrés, Maria Carmen Terencio, Miguel Payá, Angela Zampella

Journal:

Year:

2009

Language:

english

File:

PDF, 214 KB

english, 2009

23

Synthetic studies on homophymine A: stereoselective synthesis of (2R,3R,4R,6R)-3-hydroxy-2,4,6-trimethyloctanoic acid

Filomena Bellotta, Maria Valeria D'Auria, Valentina Sepe, Angela Zampella

Journal:

Year:

2009

Language:

english

File:

PDF, 215 KB

english, 2009

24

Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei

Carmen Festa, Simona De Marino, Valentina Sepe, Maria Chiara Monti, Paolo Luciano, Maria Valeria D'Auria, Cecile Débitus, Mariarosaria Bucci, Valentina Vellecco, Angela Zampella

Journal:

Year:

2009

Language:

english

File:

PDF, 254 KB

english, 2009

25

Concise synthesis of AHMHA unit in perthamide C. Structural and stereochemical revision of perthamide C

Valentina Sepe, Maria Valeria D’Auria, Giuseppe Bifulco, Raffaella Ummarino, Angela Zampella

Journal:

Year:

2010

Language:

english

File:

PDF, 313 KB

english, 2010

26

Amphiasterins: a new family of cytotoxic metabolites from the marine sponge Plakortis quasiamphiaster

Angela Zampella, Clelia Giannini, Cécile Debitus, Maria Valeria D'Auria

Journal:

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

27

Unusual sulfated marine steroids from the ophiuroid ophioderma longicaudum

Raffaele Riccio, Maria Valeria D'Auria, Luigi Minale

Journal:

Year:

1985

Language:

english

File:

PDF, 687 KB

english, 1985

28

Dysidotronic acid, a new and selective human phospholipase A2 inhibitor from the sponge Dysidea sp.

Clelia Giannini, Cécile Debitus, Inmaculada Posadas, Miguel Payá, Maria Valeria D’Auria

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

29

Isolation of callipeltins A–C and of two new open-chain derivatives of callipeltin A from the marine sponge Latrunculia sp. A revision of the stereostructure of callipeltins

Angela Zampella, Antonio Randazzo, Nicola Borbone, Sisto Luciani, Lucia Trevisi, Cécile Debitus, Maria Valeria D'Auria

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 83 KB

english, 2002

30

Studies towards the synthesis of superstolide A. Synthesis and stereochemical assignment of the C(21)C(26) fragment of superstolide A

Angela Zampella, Maria Valeria D'Auria

Journal:

Tetrahedron: Asymmetry

Year:

2001

Language:

english

File:

PDF, 106 KB

english, 2001

31

Synthetic studies on callipeltin A: stereoselective synthesis of (2R,3R,4S)-3-hydroxy-2,4,6-trimethylheptanoic acid

Angela Zampella, Maria Sorgente, Maria Valeria D'Auria

Journal:

Tetrahedron: Asymmetry

Year:

2002

Language:

english

File:

PDF, 151 KB

english, 2002

32

Stereoselective synthesis of (2R,3R,4R)-3-hydroxy-2,4,6-trimethylheptanoic acid and determination of the absolute stereochemistry of the natural product from callipeltin A

Angela Zampella, Maria Valeria D'Auria

Journal:

Tetrahedron: Asymmetry

Year:

2002

Language:

english

File:

PDF, 69 KB

english, 2002

33

Stereochemical assignment of the C23–C35 portion of sphinxolide/reidispongiolide class of natural products by asymmetric synthesis

Angela Zampella, Valentina Sepe, Rosa D'Orsi, Giuseppe Bifulco, Carla Bassarello, Maria Valeria D'Auria

Journal:

Tetrahedron: Asymmetry

Year:

2003

Language:

english

File:

PDF, 466 KB

english, 2003

34

Isolation and structural elucidation of the crellastatins I-M: cytotoxic bis-steroid derivatives from the vanuatu marine sponge Crella sp

Clelia Giannini, Angela Zampella, Cecile Debitus, Jean-Louis Menou, Christos Roussakis, Maria Valeria D'Auria

Journal:

Year:

1999

Language:

english

File:

PDF, 524 KB

english, 1999

35

The First Total Synthesis of Solomonsterol B, a Marine Pregnane X Receptor Agonist

Valentina Sepe, Raffaella Ummarino, Maria Valeria D'Auria, Barbara Renga, Stefano Fiorucci, Angela Zampella

Journal:

European Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 485 KB

english, 2012

36

Callipeltin A: sodium ionophore effect and tension development in vascular smooth muscle

Lucia Trevisi, Gabriella Cargnelli, Giulio Ceolotto, Italia Papparella, Andrea Semplicini, Angela Zampella, Maria Valeria D’Auria, Sisto Luciani

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 566 KB

english, 2004

37

Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M

Jérôme Busserolles, Miguel Payá, Maria Valeria D’Auria, Luigi Gomez-Paloma, Maria José Alcaraz

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 467 KB

english, 2005

38

Perthamides C–F, potent human antipsoriatic cyclopeptides

Carmen Festa, Simona De Marino, Valentina Sepe, Maria Valeria D’Auria, Giuseppe Bifulco, Rosa Andrés, Maria Carmen Terencio, Miguel Payá, Cécile Debitus, Angela Zampella

Journal:

Year:

2011

Language:

english

File:

PDF, 390 KB

english, 2011

39

Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei

Carmen Festa, Simona De Marino, Maria Valeria D’Auria, Maria Chiara Monti, Mariarosaria Bucci, Valentina Vellecco, Cécile Debitus, Angela Zampella

Journal:

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

40

Dysidotronic acid, a new sesquiterpenoid, inhibits cytokine production and the expression of nitric oxide synthase

Inmaculada Posadas, M.Carmen Terencio, Clelia Giannini, Maria Valeria D'Auria, Miguel Payá

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

41

Polyoxygenated steroids of marine origin

D'Auria, Maria Valeria., Minale, Luigi., Riccio, Raffaele.

Journal:

Chemical Reviews

Year:

1993

Language:

english

File:

PDF, 5.25 MB

english, 1993

42

4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity

Simona De Marino, Raffaella Ummarino, Maria Valeria D’Auria, Maria Giovanna Chini, Giuseppe Bifulco, Claudio D’Amore, Barbara Renga, Andrea Mencarelli, Sylvain Petek, Stefano Fiorucci, Angela Zampella

Journal:

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

43

Quantitative NMR-Derived Interproton Distances Combined with Quantum Mechanical Calculations of 13 C Chemical Shifts in the Stereochemical Determination of Conicasterol F, a Nuclear Receptor Ligand from Theonella swinhoei

Chini, Maria Giovanna, Jones, Catharine R., Zampella, Angela, D’Auria, Maria Valeria, Renga, Barbara, Fiorucci, Stefano, Butts, Craig P., Bifulco, Giuseppe

Journal:

Journal of Organic Chemistry

Year:

2012

Language:

english

File:

PDF, 3.45 MB

english, 2012

44

Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist

Sepe, Valentina, Ummarino, Raffaella, D'Auria, Maria Valeria, Lauro, Gianluigi, Bifulco, Giuseppe, D'Amore, Claudio, Renga, Barbara, Fiorucci, Stefano, Zampella, Angela

Journal:

Organic & Biomolecular Chemistry

Year:

2012

Language:

english

File:

PDF, 1.71 MB

english, 2012

45

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei

De Marino, Simona, Sepe, Valentina, D'Auria, Maria Valeria, Bifulco, Giuseppe, Renga, Barbara, Petek, Sylvain, Fiorucci, Stefano, Zampella, Angela

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 318 KB

english, 2011

46

Marine sponge steroids as nuclear receptor ligands

Stefano Fiorucci, Eleonora Distrutti, Giuseppe Bifulco, Maria Valeria D’Auria, Angela Zampella

Journal:

Trends in Pharmacological Sciences

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

47

Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris

Carmen Festa, Simona De Marino, Maria Valeria D'Auria, Eric Deharo, German Gonzalez, Chloe Deyssard, Sylvain Petek, Giuseppe Bifulco, Angela Zampella

Journal:

Year:

2012

Language:

english

File:

PDF, 438 KB

english, 2012

48

New antimalarial polyketide endoperoxides from the marine sponge Plakinastrella mamillaris collected at Fiji Islands

Festa, Carmen, De Marino, Simona, D’Auria, Maria Valeria, Taglialatela-Scafati, Orazio, Deharo, Eric, Petek, Sylvain, Zampella, Angela

Journal:

Year:

2013

Language:

english

File:

PDF, 362 KB

english, 2013

49

Solomonsterols A and B from Theonella swinhoei . The First Example of C-24 and C-23 Sulfated Sterols from a Marine Source Endowed with a PXR Agonistic Activity

Festa, Carmen, De Marino, Simona, D’Auria, Maria Valeria, Bifulco, Giuseppe, Renga, Barbara, Fiorucci, Stefano, Petek, Sylvain, Zampella, Angela

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.56 MB

english, 2011

50

Swinholide J, a Potent Cytotoxin from the Marine Sponge Theonella swinhoei

Marino, Simona De, Festa, Carmen, D’Auria, Maria Valeria, Cresteil, Thierry, Debitus, Cecile, Zampella, Angela

Journal:

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011